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Gabapentin, sold under the trade name Neurontin, is used to treat neuropathic pain in horses. It may be given orally or intravenously, although oral bioavailability is fairly poor (~16%), and it can produce sedation and increased drinking. [81] Gabapentin has been used for femoral neuropathy following surgery, [82] laminitis, and headshaking in ...
Additionally, horses with a hind limb lameness will tend to reduce the degree of leg use. To do so, some horses will reduce the contraction time of the gluteals on the side of the lame leg, leading to a "hip roll" or "hip dip" and appearance that the hip drops a greater degree on the side of the lame leg. [10]
Horses are best managed by only allowing short grazing periods—less than 1 hour since they can rapidly ingest grass, [18] or confining them to a limited turn-out area or by use of a grazing muzzle. Horses with severe IR, that have recurrent laminitis, are not recommended to return to pasture. Hay low in NSC is provided in place of pasture.
This sometimes leads to static laminitis, particularly if the animal is confined in a stall. [10] A notable example is the 2006 Kentucky Derby winner Barbaro. [11] Transport laminitis sometimes occurs in horses confined in a trailer or other transportation for long periods of time. Historically, the most extreme instances were of horses shipped ...
However, any horse that can store excess amounts of glycogen, usually genetic, can develop this form of ER. [1] Recurrent Exertional Rhabdomyolysis (RER) is commonly found in breeds that are high strung such as Arabians and thoroughbreds. However, any horse can develop this type of ER if it displays abnormal muscle contractions. [1]
Gabapentin is effective in treating sleep disorders such as insomnia and restless legs syndrome that are the result of an underlying illness, but comes with some risk of discontinuation and withdrawal symptoms after prolonged use at higher doses. [39] Gabapentin enhances slow-wave sleep in people with primary insomnia.
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