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Katalin "Kati" Karikó (Hungarian: Karikó Katalin, pronounced [ˈkɒrikoː ˌkɒtɒlin]; born 17 January 1955) is a Hungarian-American [2] biochemist who specializes in ribonucleic acid ()-mediated mechanisms, particularly in vitro-transcribed messenger RNA (mRNA) for protein replacement therapy. [3]
Jon Asher Wolff (September 25, 1956 – April 17, 2020) was an American geneticist.He was the lead author on a 1990 study published in the journal Science that first suggested the possibility of synthesizing mRNA in a laboratory to trigger the production of a desired protein.
Drew Weissman (born September 7, 1959) is an American physician and immunologist known for his contributions to RNA biology. Weissman is the inaugural Roberts Family Professor in Vaccine Research, director of the Penn Institute for RNA Innovation, and professor of medicine at the Perelman School of Medicine at the University of Pennsylvania (Penn).
Two pioneering scientists who created the technology behind life-saving Covid-19 vaccines have won the Nobel Prize in medicine or physiology.
Worcester Foundation for Biomedical Research: 1984 National Academy of Sciences (US) Holley, Robert: 1922–1993 Cornell University: 1965 Lasker Award, 1968 Nobel Prize in Physiology or Medicine Hurwitz, Jerard: Sloan-Kettering Institute: 1974 National Academy of Sciences (US) Jacob, François: 1920–2013 Pasteur Institute
Antisense RNA is complementary to coding mRNA and is used to trigger mRNA inactivation to prevent the mRNA from being used in protein translation. [4] RNAi-based systems use a similar mechanism, and involve the use of both small interfering RNA (siRNA) and micro RNA (miRNA) to prevent mRNA translation and/or degrade mRNA.
Linux, macOS, Unix, Windows [4] GPL and LGPL: Collaborative project Galaxy: Scientific workflow and data integration system Unix-like: Academic Free: Collaborative project GenePattern: Scientific workflow system that provides access to hundreds of genomic analysis tools Unix-like (public server); Linux, macOS, Windows: MIT: Broad Institute, UC ...
In 2007, Moore moved her research group to the Biochemistry and Molecular Pharmacology Department at the University of Massachusetts Chan Medical School (UMass Med). [ 9 ] [ 10 ] In 2011, Moore was the recipient of the American Society for Biochemistry and Molecular Biology 's William C. Rose Award [ 11 ] for excellence in mentoring.