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  2. Modafinil - Wikipedia

    en.wikipedia.org/wiki/Modafinil

    In a 2006 study, a single dose of modafinil 200 mg caused a decrease in blood prolactin levels, although it did not affect human growth hormone or thyroid-stimulating hormone. [87] [143] Since modafinil induces the activity of the CYP3A4 enzyme involved in cortisol clearance, [144] modafinil may reduce the bioavailability of hydrocortisone ...

  3. Armodafinil - Wikipedia

    en.wikipedia.org/wiki/Armodafinil

    At steady state, the systemic exposure for armodafinil is 1.8 times the exposure observed after a single dose. The concentration-time profiles of the (R)-(−)-enantiomer following a single dose of 50 mg Nuvigil or 100 mg Provigil (modafinil being a 1:1 mixture of (R)-(−)- and (S)-(−)- enantiomers

  4. List of psychotropic medications - Wikipedia

    en.wikipedia.org/wiki/List_of_psychotropic...

    Provigil - used to treat excessive sleepiness and narcolepsy Prozac ( fluoxetine ) – an antidepressant of the SSRI class Luminal ( phenobarbital ) – a barbiturate with sedative and hypnotic properties

  5. Protriptyline - Wikipedia

    en.wikipedia.org/wiki/Protriptyline

    It is used in dosages of 15 to 40 mg/day, whereas most other TCAs are used at dosages of 75 to 300 mg/day. [18] The maximum dose is 60 mg/day. [18] Therapeutic levels of protriptyline are typically in the range of 70 to 250 ng/mL (266-950 nmol/L), which is similar to that of other TCAs [19] [20] [21]

  6. Equianalgesic - Wikipedia

    en.wikipedia.org/wiki/Equianalgesic

    An equianalgesic chart is a conversion chart that lists equivalent doses of analgesics (drugs used to relieve pain). Equianalgesic charts are used for calculation of an equivalent dose (a dose which would offer an equal amount of analgesia) between different analgesics. [1]

  7. List of modafinil analogues and derivatives - Wikipedia

    en.wikipedia.org/wiki/List_of_modafinil...

    Chemical structure of modafinil.. This page lists chemical compounds similar to modafinil, known as modafinil analogues and derivatives.These are structural analogues and derivatives of modafinil, a drug that affects dopamine levels in the brain in an unusual way (atypical dopamine reuptake inhibitor or DRI).

  8. Therapeutic index - Wikipedia

    en.wikipedia.org/wiki/Therapeutic_index

    The maximum dose is used, rather than a lower dose, to reduce the number of test subjects (and, among other things, the cost of testing), to detect an effect that might occur only rarely. This type of analysis is also used in establishing chemical residue tolerances in foods. Maximum tolerated dose studies are also done in clinical trials.

  9. Eugeroic - Wikipedia

    en.wikipedia.org/wiki/Eugeroic

    Modafinil and armodafinil are thought to act as selective, weak, atypical dopamine reuptake inhibitors (DRIs). [13] [3] [4] However, additional actions are also possible and have not been ruled out. [13] Adrafinil acts as a prodrug of modafinil and hence shares its mechanism of action. [13]

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