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Synthetic oxytocin, sold under the brand name Pitocin among others, is a medication made from the peptide oxytocin. [6] [7] As a medication, it is used to cause contraction of the uterus to start labor, increase the speed of labor, and to stop bleeding following delivery. [6] For this purpose, it is given by injection either into a muscle or ...
Oxytocin is a peptide hormone and neuropeptide normally produced in the hypothalamus and released by the posterior pituitary. [4] Present in animals since early stages of evolution, in humans it plays roles in behavior that include social bonding, love, reproduction, childbirth, and the period after childbirth.
Intranasal (IN) administration, as opposed to more conventional routes, such as oral or intravenous infusion, offers an alternative method for drug delivery. This method is often the preferred method. Oxytocin (OT) is a neuropeptide that can be administered in this manner. IN delivery methods are gaining popularity due to the non-invasive ...
Intravenous or intramuscular oxytocin is the drug of choice for postpartum hemorrhage. [19] [20] Ergotamine may also be used. [2] Oxytocin helps the uterus to contract quickly and the contractions to last longer. [21] It is the first line treatment for PPH when its cause is the uterus not contracting well. [22]
Oxytocin/ergometrine (trade name Syntometrine) is an obstetric combination drug. The components are synthetically produced oxytocin, a human hormone produced in the hypothalamus, and ergometrine, an alpha-adrenergic, dopaminergic and serotonin (5-HT 2) receptor agonist. Both substances cause the uterus to contract.
The hormone oxytocin has been identified as inducing uterine contractions, and labour in general. [9] Oxytocin is produced by the body naturally and since the 1950s has also been available in synthetic pharmaceutical form. [10] [11] In either form, oxytocin stimulates uterine contractions to accelerate the process of childbirth.
The combination of dopamine, serotonin and oxytocin is already pretty dreamy, but the brain takes that natural high to the next level when you reach the big O by releasing endogenous (i.e., made ...
In Western countries, it is estimated that one-quarter of pregnant women have their labor medically induced with drug treatment. [1] Inductions are most often performed either with prostaglandin drug treatment alone, or with a combination of prostaglandin and intravenous oxytocin treatment. [1]