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A crista (/ ˈ k r ɪ s t ə /; pl.: cristae) is a fold in the inner membrane of a mitochondrion. The name is from the Latin for crest or plume , and it gives the inner membrane its characteristic wrinkled shape, providing a large amount of surface area for chemical reactions to occur on.
The end of cristae are partially closed by transmembrane protein complexes that bind head to head and link opposing crista membranes in a bottleneck-like fashion. [2] For example, deletion of the junction protein IMMT leads to a reduced inner membrane potential and impaired growth [ 3 ] and to dramatically aberrant inner membrane structures ...
Mitochondrial matrix has a pH of about 7.8, which is higher than the pH of the intermembrane space of the mitochondria, which is around 7.0–7.4. [5] Mitochondrial DNA was discovered by Nash and Margit in 1963. One to many double stranded mainly circular DNA is present in mitochondrial matrix. Mitochondrial DNA is 1% of total DNA of a cell.
The inner mitochondrial membrane divides the mitochondrial lumen into two parts: the inner border membrane, which runs parallel to the OMM, and the cristae, which are deeply twisted, multinucleated invaginations that give room for surface area enlargement and house the mitochondrial respiration apparatus.
Some excavates lack "classical" mitochondria, and are called "amitochondriate", although most retain a mitochondrial organelle in greatly modified form (e.g. a hydrogenosome or mitosome). Among those with mitochondria, the mitochondrial cristae may be tubular, discoidal, or in some cases, laminar.
Cellular respiration takes place in the cristae of the mitochondria within cells. Depending on the pathways followed, the products are dealt with in different ways. CO 2 is excreted from the cell via diffusion into the blood stream, where it is transported in three ways: Up to 7% is dissolved in its molecular form in blood plasma.
Most mutations of mitochondrial membrane transporters are autosomal recessive. Mutations to transporters within the inner mitochondrial membrane mostly affect high-energy tissues due to the disruption of oxidative phosphorylation. [4] [44] For example, decreased mitochondrial function has been linked to heart failure and hypertrophy. This ...
Amoebozoa is a major taxonomic group containing about 2,400 described species of amoeboid protists, [8] often possessing blunt, fingerlike, lobose pseudopods and tubular mitochondrial cristae. [ 7 ] [ 9 ] In traditional classification schemes, Amoebozoa is usually ranked as a phylum within either the kingdom Protista [ 10 ] or the kingdom ...