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The disputed late-life mortality deceleration law states that death rates stop increasing exponentially at advanced ages and level off to the late-life mortality plateau. A consequence of this deceleration is that there would be no fixed upper limit to human longevity — no fixed number which separates possible and impossible values of lifespan.
"The first 1000-year-old is probably only ~10 years younger than the first 150-year-old."–Aubrey de Grey, 2005 [1]. In the life extension movement, longevity escape velocity (LEV), actuarial escape velocity [2] or biological escape velocity [3] is a hypothetical situation in which one's remaining life expectancy (not life expectancy at birth) is extended longer than the time that is passing.
Life history theory has provided new perspectives in understanding many aspects of human reproductive behavior, such as the relationship between poverty and fertility. [43] A number of statistical predictions have been confirmed by social data [ citation needed ] and there is a large body of scientific literature from studies in experimental ...
Life Extension Foundation Methuselah Foundation – non-profit organization dedicated to extending the healthy human lifespan by advancing tissue engineering and regenerative medicine therapies. It was co-founded in 2003 by Aubrey de Grey and David Gobel, and is based in Springfield, Virginia, United States.
As metabolic rate increases, the lifespan of an organism is expected to decrease as a direct result. The rate at which this occurs is not fixed and thus the -45° slope in this graph is just an example and not a constant. The rate of living theory postulates that the faster an organism's metabolism, the shorter its lifespan.
For sexually reproducing planaria: "the lifespan of individual planarian can be as long as 3 years, likely due to the ability of neoblasts to constantly replace aging cells". Whereas for asexually reproducing planaria: "individual animals in clonal lines of some planarian species replicating by fission have been maintained for over 15 years".
The relationship between telomeres and longevity and changing the length of telomeres is one of the new fields of research on increasing human lifespan and even human immortality. [ 1 ] [ 2 ] Telomeres are sequences at the ends of chromosomes that shorten with each cell division and determine the lifespan of cells . [ 3 ]
The longest documented human lifespan is 122 years 164 days, the case of Jeanne Calment, who according to records was born in 1875 and died in 1997, whereas the maximum lifespan of a wildtype mouse, commonly used as a model in research on aging, is about three years. [10]