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Heartburn is a common symptom of late term pregnancy during which up to 80% of pregnant women have experienced it by the end of their third trimester. [12] Heartburn often indicates the development of gastro-esophageal reflux disease (GERD), where the lower esophageal sphincter relaxes due to elevated progesterone levels causing increased ...
Gastro-esophageal reflux disease during pregnancy—First-line drug therapy combined with lifestyle and diet modification. [ 17 ] Stress ulcer prophylaxis —The use of sucralfate rather than H 2 antagonists for stress ulcer prophylaxis, and measures to prevent aspiration , such as continuous subglottic suctioning, have been shown to reduce the ...
Heartburn is common during pregnancy having been reported in as many as 80% of pregnancies. [22] It is most often due to GERD and results from relaxation of the lower esophageal sphincter (LES), changes in gastric motility, and/or increasing intra-abdominal pressure. [23] [22] The onset of symptoms can be during any trimester of pregnancy.
Heartburn – Heartburn (Regurgitation) is a burning pain in the chest, behind the breastbone that occurs when stomach acid travel up the esophagus and causes irritation. This sometimes happens in pregnancy due to relaxation of the lower esophageal sphincter (LES), which normally keeps acidic stomach contents in the stomach. Additionally ...
Famotidine, sold under the brand name Pepcid among others, is a histamine H 2 receptor antagonist medication that decreases stomach acid production. [4] It is used to treat peptic ulcer disease, gastroesophageal reflux disease, and Zollinger-Ellison syndrome. [4]
Use in pregnancy appears to be safe, while safety during breastfeeding is unclear. [3] Esomeprazole is the (S)-(−)-enantiomer (or less specifically the S-isomer) of omeprazole. [11] It works by blocking H + /K +-ATPase in the parietal cells of the stomach. [11] It was patented in 1993 and approved for medical use in 2000. [14]
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