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The midbrain or mesencephalon is the uppermost portion of the brainstem connecting the diencephalon and cerebrum with the pons. [2] It consists of the cerebral peduncles , tegmentum , and tectum . It is functionally associated with vision, hearing, motor control, sleep and wakefulness, arousal ( alertness ), and temperature regulation.
Reticular formation: This is a large area in the midbrain that is involved in various important functions of the midbrain. In particular, it contains lower motor neurons, is involved in the pain desensitization pathway, is involved in the arousal and consciousness systems, and contains the locus coeruleus , which is involved in intensive ...
The ventral tegmental area is in the midbrain between several other major areas, some of which are described here. The mammillary bodies and the posterior hypothalamus, both included in the diencephalon, extend rostrally from the VTA. The red nucleus is situated laterally and oculomotor fibers are situated ventromedially to the VTA. [5]
The midbrain tegmentum is the part of the midbrain extending from the substantia nigra to the cerebral aqueduct in a horizontal section of the midbrain. Structures included in the midbrain tegmentum include the red nucleus, reticular formation, and substantia nigra. The red nucleus is responsible for controlling basic body and limb movements.
Stimulation of the periaqueductal gray matter of the midbrain activates enkephalin-releasing neurons that project to the raphe nuclei in the brainstem. 5-HT released from the raphe nuclei descends to the dorsal horn of the spinal cord where it forms excitatory connections with the inhibitory interneurons located in Laminae II (aka the substantia gelatinosa).
The mesolimbic pathway and its positioning in relation to the other dopaminergic pathways. The mesolimbic pathway is a collection of dopaminergic (i.e., dopamine-releasing) neurons that project from the ventral tegmental area (VTA) to the ventral striatum, which includes the nucleus accumbens (NAcc) and olfactory tubercle. [9]
executive functions; ADHD; addiction; schizophrenia; Nigrostriatal pathway: The nigrostriatal pathway transmits dopaminergic neurons from the zona compacta of the substantia nigra [8] to the caudate nucleus and putamen. The substantia nigra is located in the midbrain, while both the caudate nucleus and putamen are located in the dorsal striatum ...
Neurophilosophy – some observations on this type of approach and localization of function; Receptor cell – cells that sense external stimuli and conducted that information to the brain; Multisensory integration – organization of sensation from one's own body and the environment into usable functional outputs; Lateralization of brain function