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Inflammatory bowel disease (IBD) is a group of inflammatory conditions of the colon and small intestine, with Crohn's disease and ulcerative colitis (UC) being the principal types. [3] Crohn's disease affects the small intestine and large intestine, as well as the mouth, esophagus, stomach and the anus, whereas UC primarily affects the colon ...
It is characterized by inflammation of the small intestine, loss of microvilli structure, deficient nutrient absorption, and malnutrition. [4] Human immunodeficiency virus enteropathy; Characterized by chronic diarrhea more than one month in duration with no obvious infectious cause in an HIV-positive individual.
Long-term exposure to environmental pathogens leads to a generalized state of intestinal inflammation. Chronic inflammation leads to both functional and structural changes which alter gut permeability and ability of the intestine to absorb nutrients. [2] [3] [1] Evidence of villous atrophy in endoscopic images of the small intestine. [1]
Inflammatory bowel disease (IBD) refers to a group of chronic conditions that impact the intestines. The two primary types of IBD are Crohn’s disease and ulcerative colitis.
Early radiation enteritis is caused by cell death of the crypt epithelium and subsequent mucosal inflammation, however usually subsides after the course of radiation therapy is completed. Delayed radiation enteritis is a chronic disease which has a complex pathogenesis involving changes in the majority of the intestinal wall. [19] [20]
“When systemic and chronic inflammation accompanies these underlying diseases, it can affect multiple organ systems, manifesting as fatigue, muscle weakness, digestive disturbances, joint pain ...
Crohn's disease is a chronic inflammatory bowel disease characterized by recurrent episodes of intestinal inflammation, primarily manifesting as diarrhea and abdominal pain. Unlike ulcerative colitis , inflammation can occur anywhere in the gastrointestinal tract, though it most frequently affects the ileum and colon , involving all layers of ...
High frequency of bowel movements, weight loss, nausea, fatigue, and fever are also common during disease flares. Chronic bleeding from the GI tract, chronic inflammation, and iron deficiency often leads to anemia, which can affect quality of life. [15] The clinical presentation of ulcerative colitis depends on the extent of the disease process ...
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