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The power of twin designs arises from the fact that twins may be either identical (monozygotic (MZ), i.e. developing from a single fertilized egg and therefore sharing all of their polymorphic alleles) or fraternal (dizygotic (DZ), i.e. developing from two fertilized eggs and therefore sharing on average 50% of their alleles, the same level of genetic similarity found in non-twin siblings).
The human twin birth rate in the United States rose 76% from 1980 through 2009, from 9.4 to 16.7 twin sets (18.8 to 33.3 twins) per 1,000 births. [5] The Yoruba people have the highest rate of twinning in the world, at 45–50 twin sets (90–100 twins) per 1,000 live births, [6] [7] [8] possibly because of high consumption of a specific type of yam containing a natural phytoestrogen which may ...
A second and more common design is the twin study in which the similarity of identical and fraternal twins is used to estimate heritability. These studies can be limited by the fact that identical twins are not completely genetically identical, potentially resulting in an underestimation of heritability.
A twin study compares the concordance rate of identical twins to that of fraternal twins. This can help suggest whether a disease or a certain trait has a genetic cause. [3] Controversial uses of twin data have looked at concordance rates for homosexuality and intelligence. Other studies have involved looking at the genetic and environmental ...
The word zygosity may also be used to describe the genetic similarity or dissimilarity of twins. [6] Identical twins are monozygotic, meaning that they develop from one zygote that splits and forms two embryos. Fraternal twins are dizygotic because they develop from two separate oocytes (egg cells) that are fertilized by two separate sperm.
Fraternal twins develop from two different eggs by two different sperm -- so they can often look slightly different. Although some, like Mary Kate and Ashley Olsen, end up looking so much alike ...
Fourteen sets of twins and one set of triplets graduated June 5 from Cooper City High School in Cooper City, Florida, about 40 minutes outside of Miami. The group comprised about 6% of the 543 ...
The cause of the condition lies in conception or utero with the aggregation of two distinct zygotes or blastocysts (one of which expresses 46,XX and the other of which expresses 46,XY) into a single embryo, [4] which subsequently leads to the development of a single individual with two distinct cell lines, instead of a pair of fraternal twins.