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Administration of high-dose testosterone in men over a course of weeks can cause an increase in aggression and hypomanic symptoms, though these were seen in only a minority of subjects. [15] Acute high-dose anabolic-androgenic steroid administration in males attenuates endogenous sex hormone production and affects the thyroid hormone axis.
Many transgender men report an increased energy level, decreased need for sleep, and increased alertness after testosterone therapy. In cisgender men, abnormally high or low levels of testosterone are both associated with insulin resistance (which eventually can result in Type II diabetes).
The discovery of testosterone in 1935 led to the development of testosterone replacement therapy (TRT), which has since become a cornerstone treatment for male hypogonadism. Additionally, hormone replacement therapy (HRT) for women has advanced, providing solutions for conditions such as menopause-related hypogonadism. [ 9 ]
Conversely, “with too much testosterone, women often have acne, too much hair on the body, hair loss on the head, high blood pressure, elevated cholesterol, skipped cycles, or problems ...
A booming industry of men's health clinics offers men in their 20s, 30s, and 40s testosterone therapy to optimize their bodies. Doctors are skeptical. Young men are getting testosterone boosts to ...
What’s more, men with low levels of testosterone at baseline saw an increase in testosterone when taking 5-alpha-reductase inhibitors, but men with high levels of testosterone at baseline didn ...
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