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These two forms of vitamin D are metabolized in the liver and stored as 25-hydroxyvitamin D. [4] Before biological use, the storage form must be converted into an active form. One common active form is 1,25-dihydroxyvitamin D. [4] The term vitamin D in this article means cholecalciferol, ergocalciferol, 25-hydroxyvitamin D, and the active forms ...
Type 3 diabetes is a proposed pathological linkage between Alzheimer's disease and certain features of type 1 and type 2 diabetes. [1] Specifically, the term refers to a set of common biochemical and metabolic features seen in the brain in Alzheimer's disease, and in other tissues in diabetes; [1] [2] it may thus be considered a "brain-specific type of diabetes."
In particular, vitamin D supplementation has been shown to have positive effects on people with type 1 diabetes. [92] [93] Vitamin D has also been suggested to act on immune system and modulate inflammatory responses by influencing proliferation and differentiation of different immune cells.
A neuron observed under an optical microscope. Neuroprotection refers to the relative preservation of neuronal structure and/or function. [1] In the case of an ongoing insult (a neurodegenerative insult) the relative preservation of neuronal integrity implies a reduction in the rate of neuronal loss over time, which can be expressed as a differential equation.
Since vitamin D is a fat-soluble vitamin, too much can put you at serious risk for toxicity including adverse side effects like kidney stones and high calcium levels in the blood.
Vitamin D insufficiency is characterized by a blood 25(OH)D level between 12–20 ng/mL (30–50 nmol/liter). [2] [21] It is estimated that one billion adults worldwide are either vitamin D insufficient or deficient, including those in developed countries across Europe. [22]
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