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Drug-induced fever is a symptom of an adverse drug reaction wherein the administration of drugs intended to help a patient causes a hypermetabolic state resulting in fever. The drug may interfere with heat dissipation peripherally, increase the rate of metabolism , evoke a cellular or humoral immune response , mimic endogenous pyrogen , or ...
Some drugs cause excessive internal heat production. [2] The rate of drug-induced hyperthermia is higher where use of these drugs is higher. [2] Many psychotropic medications, such as selective serotonin reuptake inhibitors (SSRIs), monoamine oxidase inhibitors (MAOIs), and tricyclic antidepressants, can cause hyperthermia. [2]
Hypothermia is the cause of at least 1,500 deaths a year in the United States. [2] It is more common in older people and males. [5] One of the lowest documented body temperatures from which someone with accidental hypothermia has survived is 12.7 °C (54.9 °F) in a 2-year-old boy from Poland named Adam. [6]
When two drugs affect each other, it is a drug–drug interaction (DDI). The risk of a DDI increases with the number of drugs used. [1] A large share of elderly people regularly use five or more medications or supplements, with a significant risk of side-effects from drug–drug interactions. [2] Drug interactions can be of three kinds:
Simplified control circuit of human thermoregulation. [8]The core temperature of a human is regulated and stabilized primarily by the hypothalamus, a region of the brain linking the endocrine system to the nervous system, [9] and more specifically by the anterior hypothalamic nucleus and the adjacent preoptic area regions of the hypothalamus.
In most people with malignant hyperthermia susceptibility, they have few or no symptoms unless they are exposed to a triggering agent. The most common triggering agents are volatile anesthetic gases, such as halothane , sevoflurane , desflurane , isoflurane , enflurane or the depolarizing muscle relaxants suxamethonium and decamethonium used ...
The College Football Playoff got underway Friday but the main course is spread out through Saturday. Three first-round games will be played across three separate campus sites from State College ...
[2] [3] They emphasize deprescribing medications that are unnecessary, which helps to reduce the problems of polypharmacy, drug interactions, and adverse drug reactions, thereby improving the risk–benefit ratio of medication regimens in at-risk people. [4] The criteria are used in geriatrics clinical care to monitor and improve the quality of ...