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Chronic lymphocytic leukemia; Other names: B-cell chronic lymphocytic leukemia (B-CLL) [1] Peripheral blood smear showing CLL cells: Specialty: Hematology and oncology: Symptoms: Early: None [2] Later: Non-painful lymph nodes swelling, feeling tired, fever, weight loss, night sweats [2] Usual onset: Older than 50 [3] Risk factors
Glucose Tolerance and Random Plasma Glucose Test. An oral glucose tolerance test checks how your body responds to glucose. Your blood glucose levels are measured before you consume 75 grams of ...
Insulin resistance, or low insulin sensitivity, happens when cells throughout the body don’t respond properly to the hormone insulin, especially cells in muscles, fat and the liver.
As long as the pancreatic beta cells are able to sense the glucose level and produce insulin, the amount of insulin secreted is usually the amount required to maintain a fasting blood glucose between 70 and 100 mg/dL (3.9–5.6 mmol/L) and a non-fasting glucose level below 140 mg/dL (<7.8 mmol/L).
CLL/SLL is the most common adult leukemia in Western countries, accounting for 1.2% of the new cancers diagnosed each year in the United States. It usually occurs in older adults (median age at diagnosis 70) and follows an indolent course over many years. [11] About 1-10% of CLL/SLLs develop a Richter's transformation at a rate of 0.5–1% per ...
Manifestations of hyperinsulinemic hypoglycemia vary by age and severity of the hypoglycemia. In general, most signs and symptoms can be attributed to (1) the effects on the brain of insufficient glucose (neuroglycopenia) or (2) to the adrenergic response of the autonomic nervous system to hypoglycemia.
The diagnosis of MBL in these patients depends on finding 0.5-5x10 9 monoclonal B cells that express the makers characteristic of CLL/SLL MLB, atypical CLL/SLL MLB, non-CLL/SLL MLB, or MLB-MZ. [3] However, individuals with CBL-MZ commonly present with B-cell blood counts that are extremely high (>4.0x10 9 ; range 3.0x10 9 /L to 37.1x10 9 /L ...
T-PLL is a very rare leukemia, primarily affecting adults over the age of 30. It represents 2% of all small lymphocytic leukemias in adults. [2] Other names include T-cell chronic lymphocytic leukemia, "knobby" type of T-cell leukemia, and T-prolymphocytic leukemia/T-cell lymphocytic leukemia. [1]