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  2. Spironolactone - Wikipedia

    en.wikipedia.org/wiki/Spironolactone

    Spironolactone can cause hyperkalemia, or high blood potassium levels. [111] Rarely, this can be fatal. [111] Of people with heart disease prescribed typical dosages of spironolactone, 10 to 15% develop some degree of hyperkalemia, and 6% develop severe hyperkalemia. [111] At a higher dosage, a rate of hyperkalemia of 24% has been observed. [119]

  3. Pharmacodynamics of spironolactone - Wikipedia

    en.wikipedia.org/wiki/Pharmacodynamics_of...

    Androgen receptor antagonistic potency of spironolactone, cyproterone acetate, and flutamide in castrated male rats treated with exogenous testosterone (as measured by inhibition of androgen-dependent ventral prostate weight). [27] Spironolactone is an antagonist of the AR, the biological target of androgens like testosterone and DHT.

  4. Does Low Estrogen Cause Hair Loss? - AOL

    www.aol.com/does-low-estrogen-cause-hair...

    For those with signs of hyperandrogenism (excessive androgen hormones) and other hormonal imbalances, spironolactone may be an effective treatment for female pattern hair loss. Spironolactone ...

  5. Hyperaldosteronism - Wikipedia

    en.wikipedia.org/wiki/Hyperaldosteronism

    Treatment includes removing the causative agent (such as licorice), a high-potassium, low-sodium diet (for primary) and high-sodium diet (for secondary), spironolactone and eplerenone, potassium-sparing diuretics that act as aldosterone antagonists, and surgery, depending on the cause. [11] For adrenal adenoma, sometimes surgery is performed.

  6. Can Taking Antidepressants Cause Weight Loss? - AOL

    www.aol.com/taking-antidepressants-cause-weight...

    In fact, there are even some antidepressants that cause weight loss. Below, we’ve explained how certain antidepressants may affect your appetite, eating habits and body weight.

  7. Are Diabetes Drugs Really Safe (& Reliable) for Weight Loss?

    www.aol.com/diabetes-drugs-really-safe-reliable...

    GLP-1 drugs for weight loss and type 2 diabetes include dulaglutide, liraglutide, and semaglutide. GIP/GLP-1s. These are dual-acting, meaning they target two receptors in the body: gastric ...

  8. 7α-Thiomethylspironolactone - Wikipedia

    en.wikipedia.org/wiki/7α-Thiomethylspironolactone

    Spironolactone is a prodrug with a short terminal half-life of 1.4 hours. [5] [6] [7] The active metabolites of spironolactone have extended terminal half-lives of 13.8 hours for 7α-TMS, 15.0 hours for 6β-OH-7α-TMS, and 16.5 hours for canrenone, and accordingly, these metabolites are responsible for the therapeutic effects of the drug. [5] [6]

  9. Weight-loss, diabetes drugs linked to vision problems in ...

    www.aol.com/weight-loss-diabetes-drugs-linked...

    Popular drugs for diabetes and weight loss could have an unexpected side effect. Glucagon-like peptide 1 (GLP-1) receptor agonists, which are used to treat type 2 diabetes and/or obesity, were ...

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