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  2. Nanoparticle drug delivery - Wikipedia

    en.wikipedia.org/wiki/Nanoparticle_drug_delivery

    Nanoparticle drug delivery systems are engineered technologies that use nanoparticles for the targeted delivery and controlled release of therapeutic agents. The modern form of a drug delivery system should minimize side-effects and reduce both dosage and dosage frequency. Recently, nanoparticles have aroused attention due to their potential ...

  3. Gold nanoparticles in chemotherapy - Wikipedia

    en.wikipedia.org/wiki/Gold_nanoparticles_in...

    Some of the properties that gold nanoparticles possess, such as small size, non-toxicity and non-immunogenicity make these molecules useful candidates for targeted drug delivery systems. With tumor-targeting delivery vectors becoming smaller, the ability to by-pass the natural barriers and obstacles of the body becomes more probable. To ...

  4. Targeted drug delivery - Wikipedia

    en.wikipedia.org/wiki/Targeted_drug_delivery

    The goal of a targeted drug delivery system is to prolong, localize, target and have a protected drug interaction with the diseased tissue. The conventional drug delivery system is the absorption of the drug across a biological membrane, whereas the targeted release system releases the drug in a dosage form.

  5. Nanomedicine - Wikipedia

    en.wikipedia.org/wiki/Nanomedicine

    These devices are faster and more sensitive than typical drug delivery. [15] The efficacy of drug delivery through nanomedicine is largely based upon: a) efficient encapsulation of the drugs, b) successful delivery of drug to the targeted region of the body, and c) successful release of the drug. [16] Several nano-delivery drugs were on the ...

  6. Nanoparticles for drug delivery to the brain - Wikipedia

    en.wikipedia.org/wiki/Nanoparticles_for_drug...

    This was a huge breakthrough in the nanoparticle drug delivery field, and it helped advance research and development toward clinical trials of nanoparticle delivery systems. Nanoparticles range in size from 10 - 1000 nm (or 1 μm) and they can be made from natural or artificial polymers , lipids , dendrimers , and micelles .

  7. Nanocarrier - Wikipedia

    en.wikipedia.org/wiki/Nanocarrier

    Nanocarriers are useful in the drug delivery process because they can deliver drugs to site-specific targets, allowing drugs to be delivered in certain organs or cells but not in others. Site-specificity is a major therapeutic benefit as it prevents drugs from being delivered to the wrong places.

  8. Magnetic nanoparticles in drug delivery - Wikipedia

    en.wikipedia.org/wiki/Magnetic_nanoparticles_in...

    In this drug delivery system, after the drug reaches the target site and tumor cell uptake is complete, an external magnetic field is applied causing a magnetothermal effect, raising the tumor cells' temperature and further promoting drug uptake.

  9. Lipid-based nanoparticle - Wikipedia

    en.wikipedia.org/wiki/Lipid-based_nanoparticle

    In 2018, the FDA approved Alnylam's siRNA drug Onpattro , the first drug to use LNPs as the drug delivery system. [ 4 ] [ 6 ] By that point in time, siRNA drug developers like Alnylam were already looking at other options for future drugs like chemical conjugate systems , but during the 2010s, the earlier research into using LNPs for siRNA ...

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