Search results
Results from the WOW.Com Content Network
Elimination half-life: 4 h to 11 h (adults, ... Vancomycin is a glycopeptide antibiotic ... Measuring vancomycin concentrations to calculate doses optimizes therapy ...
It was proposed to be used instead of AUC in animal-to-human dose translation, as computer simulation shows that it could cope better with half-life and dosing schedule variations than AUC. This is an example of a PK/PD model, which combines pharmacokinetics and pharmacodynamics. [13]
In pharmacology, the volume of distribution (V D, also known as apparent volume of distribution, literally, volume of dilution [1]) is the theoretical volume that would be necessary to contain the total amount of an administered drug at the same concentration that it is observed in the blood plasma. [2]
Absorption half-life 1 h, elimination half-life 12 h. Biological half-life ( elimination half-life , pharmacological half-life ) is the time taken for concentration of a biological substance (such as a medication ) to decrease from its maximum concentration ( C max ) to half of C max in the blood plasma .
t 1/2 is the half-life time of the drug, which is the time needed for the plasma drug concentration to drop to its half Therefore, the amount of drug present in the body at time t A t {\displaystyle A_{t}} is;
After a year filled with animated inner emotions, mutants, aliens, gladiators and witches, the new year will bring a crop of new (or, newly revisited) movies to choose from, as always.
For comparison, adult king penguins usually weigh between 31 and 37 pounds. Pesto is the biggest chick Sea Life Melbourne has ever had. The aquarium put Pesto on public display in April.
It is possible to calculate the amount of a drug in the blood plasma that has a real potential to bring about its effect using the formula: D e = B ⋅ D a {\displaystyle De=B\cdot Da\,} where De is the effective dose , B bioavailability and Da the administered dose.