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A one-time dose of fluconazole by mouth is 90% effective in treating a vaginal yeast infection. [70] For severe nonrecurring cases, several doses of fluconazole is recommended. [20] Local treatment may include vaginal suppositories or medicated douches. Other types of yeast infections require different dosing.
Fluconazole was patented in 1981 and came into commercial use in 1988. [7] It is on the World Health Organization's List of Essential Medicines. [8] Fluconazole is available as a generic medication. [5] In 2022, it was the 160th most commonly prescribed medication in the United States, with more than 3 million prescriptions. [9] [10]
These medications come as creams, gels, lotions, ointments, powders, shampoos, tinctures and sprays. Most antifungal drugs induce fungal cell death by destroying the cell wall of the fungus. These drugs inhibit the production of ergosterol, which is a fundamental component of the fungal cell membrane and wall.
Vaginal yeast infections are due to excessive growth of Candida. [1] These yeast are normally present in the vagina in small numbers. [1] Vaginal yeast infections are typically caused by the yeast species Candida albicans. Candida albicans is a common fungus often harbored in the mouth, digestive tract, or vagina without causing adverse ...
It is commonly used in hospitals as an antiseptic. It is much more strongly antibacterial than antifungal, requiring at least a 10 times higher concentration to kill yeast compared to gram negative bacteria [24] Chlorophetanol; Diiodohydroxyquinoline (Iodoquinol) Flucytosine (5-fluorocytosine) – an antimetabolite pyrimidine analog [25] Fumagillin
If you have a yeast infection, the burning and pain, plus the discomfort of thick discharge, is unpleasant to deal with—to say the least. One in 20 women get recurrent yeast infections, which ...
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