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Bravecto 1-Month was approved by the FDA in November 2024 for the addition of the indication for the treatment and control of Haemaphysalis longicornis (Asian longhorned tick) infestations for one month in dogs and puppies eigjht weeks of age and older, and weighing 4.4 pounds (2.0 kg) or greater. [26] [27]
The reagent was used in trifluoromethylation of a thiophenolate. S-(trifluoromethyl)dibenzothiophenium tetrafluoroborate is a commercially available and known trifluoromethylation reagent based on the same principle first documented in 1990. [64] [65] In this type of compound sulfur has been replaced by oxygen, selenium and tellurium.
Sulfoxaflor is used as a systemic insecticide. Trifluralin, as with several dinitritroaniline herbicides, is a trifluoromethyl herbicide. Fluazifop is another, a phenoxy herbicide. The trifluoromethyl group can also be added to change the solubility of molecules containing other groups of interest.
Crisdesalazine (INN Tooltip International Nonproprietary Name; developmental code name AAD-2004) is a microsomal prostaglandin E2 synthase-1 (mPGES-1) inhibitor and free radical scavenger which is under development for the treatment of Alzheimer's disease, amyotrophic lateral sclerosis (ALS), depressive disorders, Parkinson's disease, and spinal muscular atrophy.
Lotilaner, sold under the brand name Credelio among others, is a veterinary medication used to control fleas and ticks in dogs and cats. [2] [3] [4] [12] It is indicated for the treatment and prevention of flea infestations (Ctenocephalides felis) and for the treatment and control of tick infestations including lone star tick (Amblyomma americanum), American dog tick (Dermacentor variabilis ...
Fipronil (IUPAC name 5-amino-1-[2,6-dichloro-4-(trifluoromethyl)phenyl]-4-(trifluoromethylsulfinyl)pyrazole-3-carbonitrile [1]) is a white, solid powder with a moldy odor. It is degraded slightly by sunlight, stable at normal temperatures for one year, and is not stable in presence of metal ions .
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