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  2. Apixaban - Wikipedia

    en.wikipedia.org/wiki/Apixaban

    Apixaban is recommended by the National Institute for Health and Clinical Excellence for the prevention of stroke and systemic embolism in people with non-valvular atrial fibrillation and at least one of the following risk factors: prior stroke or transient ischemic attack, age 75 years or older, diabetes, or symptomatic heart failure.

  3. Direct factor Xa inhibitors - Wikipedia

    en.wikipedia.org/wiki/Direct_factor_Xa_inhibitors

    Side effects may include bleeding, most commonly from the nose, gastrointestinal tract (GI) or genitourinary system. [2] Compared to the risk of bleeding with warfarin use, direct factor Xa inhibitors have a higher risk of GI bleeding, but lower risk of bleeding in the brain. [2]

  4. Discovery and development of direct Xa inhibitors - Wikipedia

    en.wikipedia.org/wiki/Discovery_and_development...

    The p-methoxy group of apixaban connects to S1 pocket of FXa but does not appear to have any interaction with any residues in this region of FXa. The pyrazole N-2 nitrogen atom of apixaban interacts with Gln-192 and the carbonyl oxygen interacts with Gly-216. The phenyl lactam group of apixaban is positioned between Tyr-99 and Phe-174 and due ...

  5. 15 Alternatives to Ozempic for Weight Loss - AOL

    www.aol.com/15-alternatives-ozempic-weight-loss...

    Research shows that participants taking a 3mg daily dose of liraglutide for a year experienced weight loss, but liraglutide led to even more weight loss when combined with increased physical activity.

  6. Does Medicare cover Ozempic? Yes — but it depends on your Rx

    www.aol.com/finance/does-medicare-cover-ozempic...

    The average cost Medicare Part D paid per dose was $468.24, increased from $452.72 in 2021. ... Does Medicare cover diabetes self-management training? Medicare Part B covers diabetes self ...

  7. Diabetes medication - Wikipedia

    en.wikipedia.org/wiki/Diabetes_medication

    Drugs used in diabetes treat diabetes mellitus by decreasing glucose levels in the blood. With the exception of insulin , most GLP-1 receptor agonists ( liraglutide , exenatide , and others), and pramlintide , all diabetes medications are administered orally and are thus called oral hypoglycemic agents or oral antihyperglycemic agents.

  8. Obesity Rates in the U.S. Drop for the First Time in a Decade ...

    www.aol.com/obesity-rates-u-drop-first-204508332...

    A recent study found that 6% of adults in the U.S. — or 1 in 8 — have taken the medication. While the decrease is an "encouraging reversal," the study says "obesity remains a considerable ...

  9. Anticoagulant - Wikipedia

    en.wikipedia.org/wiki/Anticoagulant

    An anticoagulant, commonly known as a blood thinner, is a chemical substance that prevents or reduces the coagulation of blood, prolonging the clotting time. [1] Some occur naturally in blood-eating animals, such as leeches and mosquitoes, which help keep the bite area unclotted long enough for the animal to obtain blood.

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