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Choriocarcinoma is a malignant, trophoblastic [1] cancer, usually of the placenta. It is characterized by early hematogenous spread to the lungs. It is characterized by early hematogenous spread to the lungs.
The choriocarcinoma has 2 significant subtypes including gestational and non-gestational and they are differentiated by their different biological feature and prognosis. [4] Signs and symptoms of GTN will appear vary from person to person and depending upon the type of the disease.
Gestational choriocarcinoma is a form of gestational trophoblastic neoplasia, which is a type of gestational trophoblastic disease (GTD), that can occur during pregnancy. It is a rare disease where the trophoblast , a layer of cells surrounding the blastocyst , undergoes abnormal developments, leading to trophoblastic tumors .
Women with a hydatidiform mole have an excellent prognosis. Women with a malignant form of GTD usually have a very good prognosis. [34] Choriocarcinoma, for example, is an uncommon, yet almost always curable cancer. Although choriocarcinoma is a highly malignant tumour and a life-threatening disease, it is very sensitive to chemotherapy.
A micrograph showing a choriocarcinoma spread to the lung [13] Choriocarcinomas are exceptionally rare which account for 2.1%-3.4% of all OGCTs. [ 14 ] Under gross examination, the syncytiotrophoblast cells are aligned in a plexiform arrangement with the mononucleated cytotrophoblast cells surrounding the foci of the hemorrhage. [ 1 ]
IBS symptoms in women can also be triggered or worsened by menstruation, though the reason why isn't completely clear. Stress can also spark symptoms of IBS. "Some people say the GI tract is a ...
A molar pregnancy, also known as a hydatidiform mole, is an abnormal form of pregnancy in which a non-viable fertilized egg implants in the uterus.It falls under the category of gestational trophoblastic diseases. [1]
Jessica Leeds . Her account: More than 30 years ago, Leeds was traveling for work when she sat next to Trump on a flight to New York. Leeds, who is now 74, told The New York Times that she and Trump spoke for a bit, then about 45 minutes into the flight he lifted the armrest between them and began to grab her breasts and put his hand up her skirt.