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Access to the previously invisible world opened the eyes and the minds of the researchers of the seventeenth century. Antonie van Leeuwenhoek investigated diverse bacteria of various shapes, fungi, and protozoa, which he called animalcules, mainly from water, mud, and dental plaque samples, and discovered biofilms as a first indication of microorganisms interacting within complex communities.
The Human Microbiome Project (HMP) was a United States National Institutes of Health (NIH) research initiative to improve understanding of the microbiota involved in human health and disease. Launched in 2007, [ 1 ] the first phase (HMP1) focused on identifying and characterizing human microbiota.
In 2014, the Earth Microbiome project proposed a broad initiative to identify the diversity and importance of the microbiota in different ecosystems across the planet, including free-living microbiota (in water and terrestrial systems) and host associated-microbiota (associated with plants and animals). [7]
A microorganism, or microbe, [a] is an organism of microscopic size, which may exist in its single-celled form or as a colony of cells.. The possible existence of unseen microbial life was suspected from ancient times, such as in Jain scriptures from sixth century BC India.
Jeffrey Dean Leach (born 1967 in Boston, Texas, known as Jeff Leach) is an American businessman and microbiome researcher from Texas. [1] He is known for his work on the gut microbiome of the Hadza hunter gatherers, [2] founding the Human Food Project, publishing archeology magazines, deceptive business practices, being accused of sexual assault, and founding the Naked Pizza restaurant chain.
[33] [34] The ways the microbiome influences human and animal health, as well as methods to influence the microbiome are active areas of research. [35] Research has suggested that microorganisms could be useful in the treatment of cancer. Various strains of non-pathogenic clostridia can infiltrate and replicate within solid tumors. Clostridial ...
The microbiome of household dust is correlated to the childhood risk of allergy, asthma and phenotypes connected to these ailments. [63] [64] [65] The impact of the microbiome of the built environment on the risk of allergy and asthma and other inflammatory or immune conditions is a possible mechanism underlying what is known as the hygiene ...
Graphic depicting the human skin microbiota, with relative prevalences of various classes of bacteria. The human microbiome is the aggregate of all microbiota that reside on or within human tissues and biofluids along with the corresponding anatomical sites in which they reside, [1] [2] including the gastrointestinal tract, skin, mammary glands, seminal fluid, uterus, ovarian follicles, lung ...