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Fexofenadine, sold under the brand name Allegra among others, [10] is an antihistamine pharmaceutical drug used in the treatment of allergy symptoms, such as hay fever and urticaria. [ 11 ] Therapeutically, fexofenadine is a selective peripheral H 1 blocker .
The first H 1 receptor antagonists were discovered in the 1930s and were marketed in the 1940s. [22] Piperoxan was discovered in 1933 and was the first compound with antihistamine effects to be identified. [22] Piperoxan and its analogues were too toxic to be used in humans. [22]
Allergic rhinitis, of which the seasonal type is called hay fever, is a type of inflammation in the nose that occurs when the immune system overreacts to allergens in the air. [6] It is classified as a type I hypersensitivity reaction . [ 8 ]
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Common side effects of glucocorticoids include fluid retention, mood changes and weight gain. The side effects are associated with the dosage, type of drug used and the duration of treatment. Systemic corticosteroids are not considered first-line therapy for chronic management due to common and significant risks of adverse reactions.
There’s also something called a subacute cough, which can last from three to eight weeks, says Jairo Barrantes-Perez, M.D., assistant professor of pulmonary medicine at Baylor College of Medicine.
For his patients who have allergies, Lizarzaburu suggests taking an over-the-counter antihistamine such as loratadine, fexofenadine or cetirizine a few days before turning on their heating system.
Bilastine is an antihistamine medication used to treat hives (), allergic rhinitis and itchy inflamed eyes (allergic conjunctivitis) caused by an allergy. [6] It is a second-generation antihistamine and takes effect by selectively inhibiting the histamine H 1 receptor, preventing these allergic reactions. [7]
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