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Topical atropine is used as a cycloplegic, to temporarily paralyze the accommodation reflex, and as a mydriatic, to dilate the pupils. [15] Atropine degrades slowly, typically wearing off in 7 to 14 days, so it is generally used as a therapeutic mydriatic, whereas tropicamide (a shorter-acting cholinergic antagonist) or phenylephrine (an α-adrenergic agonist) is preferred as an aid to ...
Cyclopentolate, Atropine, Tropicamide, and Homatropine are the typical cycloplegic eye drops used once daily to treat spasm of accommodation by relaxing the ciliary muscle. One side effect is blurred vision since these induce dilation.
[102] [103] These treatments include pirenzepine gel, cyclopentolate eye drops, and atropine eye drops. While these treatments were shown to be effective in slowing the progression of myopia and reducing eyeball elongation associated with the condition, side effects included light sensitivity and near blur. [102] [104]
Amblyopia treatment in older children: This study aimed to evaluate whether children older than 7 years with amblyopia could benefit from the treatments used in younger children (prescription eyeglasses, patching, and atropine eye drops). The results showed that older children whose amblyopia was not corrected with eyeglasses alone can benefit ...
Cycloplegic drugs are generally muscarinic receptor antagonists such as atropine, cyclopentolate, homatropine, scopolamine and tropicamide.
Treatment of strabismic or anisometropic amblyopia consists of correcting the optical deficit (wearing the necessary spectacle prescription) and often forcing use of the amblyopic eye, by patching the good eye, or instilling topical atropine in the good eye, or both. [16]: 130 [33] Atropine appears to result in similar outcomes to patching.
Some studies have shown that vision therapy, often combined with patching or atropine eye drops, can improve visual acuity and stereopsis (depth perception) in individuals with amblyopia. The Pediatric Eye Disease Investigator Group (PEDIG) has conducted several studies that support the use of vision therapy as an effective treatment option for ...
Organophosphate based nerve agent poisoning, such as VX, sarin, tabun, and soman (atropine is favoured in conjunction with an oxime, usually pralidoxime) [6] [7] Anticholinergics generally have antisialagogue effects (decreasing saliva production), and most produce some level of sedation, both being advantageous in surgical procedures.
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