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  2. Rate of infusion - Wikipedia

    en.wikipedia.org/wiki/Rate_of_infusion

    In pharmacokinetics, the rate of infusion (or dosing rate) refers not just to the rate at which a drug is administered, but the desired rate at which a drug should be administered to achieve a steady state of a fixed dose which has been demonstrated to be therapeutically effective. Abbreviations include K in, [1] K 0, [2] or R 0.

  3. Instrumental variables estimation - Wikipedia

    en.wikipedia.org/wiki/Instrumental_variables...

    One computational method which can be used to calculate IV estimates is two-stage least squares (2SLS or TSLS). In the first stage, each explanatory variable that is an endogenous covariate in the equation of interest is regressed on all of the exogenous variables in the model, including both exogenous covariates in the equation of interest and ...

  4. Area under the curve (pharmacokinetics) - Wikipedia

    en.wikipedia.org/wiki/Area_under_the_curve...

    Absolute bioavailability refers to the bioavailability of a drug when administered via an extravascular dosage form (i.e. oral tablet, suppository, subcutaneous, etc.) compared with the bioavailability of the same drug administered intravenously (IV). This is done by comparing the AUC of the non-intravenous dosage form with the AUC for the drug ...

  5. Elimination rate constant - Wikipedia

    en.wikipedia.org/wiki/Elimination_rate_constant

    The solution of this differential equation is useful in calculating the concentration after the administration of a single dose of drug via IV bolus injection: = C t is concentration after time t; C 0 is the initial concentration (t=0) K is the elimination rate constant

  6. Drip chamber - Wikipedia

    en.wikipedia.org/wiki/Drip_chamber

    For a given drip chamber (when the fluid drips from the hole into the chamber) drop factor means number of drops per ml of the IV fluid. Flow rate can be calculated with the help of the observations from the drip chamber and its drop factor. The unit of flow rate is gtts/min, where gtts means guttae (Latin plural noun meaning “drops”).

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  8. Loading dose - Wikipedia

    en.wikipedia.org/wiki/Loading_dose

    The required loading dose may then be calculated as = For an intravenously administered drug, the bioavailability F will equal 1, since the drug is directly introduced to the bloodstream.

  9. What is a factor rate and how to calculate it - AOL

    www.aol.com/finance/factor-rate-calculate...

    How to calculate a factor rate. Using the factor rate provided by the lender, you can quickly calculate the cost of the borrowed funds. For example, if you borrowed $100,000 with a factor rate of ...