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Homeodomain-only protein is a protein that in humans is encoded by the HOPX gene. [5] It is an important regulator of cardiac development [ 6 ] and a marker of hippocampal neural stem cells . [ 7 ] [ 8 ]
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The protein kinase domain is 330 amino acids long and is located near the N-terminus of the protein. [ 23 ] [ 24 ] In addition to its kinase domain, HIPK2 has two nuclear localization signals, [ 25 ] a SUMO interaction motif, [ 25 ] an auto-inhibitory domain [ 23 ] a transcriptional co-repression domain, [ 13 ] and several interaction domains ...
Homeobox genes encode homeodomain protein products that are transcription factors sharing a characteristic protein fold structure that binds DNA to regulate expression of target genes. [ 3 ] [ 4 ] [ 2 ] Homeodomain proteins regulate gene expression and cell differentiation during early embryonic development, thus mutations in homeobox genes can ...
The same Hox protein can act as a repressor at one gene and an activator at another. The ability of Hox proteins to bind DNA is conferred by a part of the protein referred to as the homeodomain. The homeodomain is a 60-amino-acid-long DNA-binding domain (encoded by its corresponding 180-base-pair DNA sequence, the homeobox
OhioHealth Riverside Methodist Hospital is the largest member hospital of OhioHealth, a not-for-profit, faith-based healthcare system located in Columbus, Ohio.. As a regional tertiary care hospital, Riverside Methodist is host to a number of specialty centers and services, including Neuroscience and Stroke, Heart and Vascular, Maternity and Women's Health, Cancer Care, Trauma Center II, Hand ...
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15394 Ensembl ENSG00000105991 ENSMUSG00000029844 UniProt P49639 P09022 RefSeq (mRNA) NM_153620 NM_005522 NM_010449 NM_001311118 RefSeq (protein) NP_005513 NP_705873 n/a Location (UCSC) Chr 7: 27.09 – 27.1 Mb Chr 6: 52.13 – 52.14 Mb PubMed search Wikidata View/Edit Human View/Edit Mouse Homeobox protein Hox-A1 is a protein that in humans is encoded by the HOXA1 gene. Gene Two transcript ...
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