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  2. Viagra: What It Treats & Its Side Effects ( Plus What It Was ...

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    Studies have shown a 70 to 80 percent success rate in patients who use this treatment. ... potentially causing heart failure. Viagra can help reduce blood pressure in the lungs within its role as ...

  3. Can You Take Viagra With High Blood Pressure? - AOL

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    Life-threatening problems can result when drug interactions between your daily medications cause side effects, and nowhere might that be more clear than with Viagra and high blood pressure.

  4. 5 Must-Know Tips Before Taking Sildenafil 100mg - AOL

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    Sildenafil side effects are generally mild and fade over time, but they occur more frequently at 100mg than 25mg and 50mg, respectively. ... Heart problems like pulmonary arterial hypertension or ...

  5. Sildenafil - Wikipedia

    en.wikipedia.org/wiki/Sildenafil

    Sildenafil, sold under the brand name Viagra among others, is a medication used to treat erectile dysfunction and pulmonary arterial hypertension. [4] [8] It is also sometimes used off-label for the treatment of certain symptoms in secondary Raynaud's phenomenon. [9] It is unclear if it is effective for treating sexual dysfunction in females. [8]

  6. What Is the Safest ED Medication? - AOL

    www.aol.com/safest-ed-medication-105700669.html

    Sildenafil. The active ingredient in Viagra, sildenafil is the most well-known medication for ED. ... Physical causes include heart and blood vessel disease, diabetes, atherosclerosis (clogged ...

  7. Discovery and development of phosphodiesterase 5 inhibitors

    en.wikipedia.org/wiki/Discovery_and_development...

    Sildenafil was initially introduced for clinical trial in 1989. It was the result of extensive research on chemical agents targeting PDE5 that could be effective in treatment of coronary heart disease. [22] Sildenafil did not prove effective for coronary heart disease but an interesting side effect was discovered, a penile erection.

  8. 4 Common ED Pills: Weighing the Pros & Cons of Each - AOL

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    The relatively short duration of sildenafil can also mean the side effects are short-lived. Finally, sildenafil is a good ED treatment from a cost perspective. ... (high blood pressure), heart ...

  9. PDE5 inhibitor - Wikipedia

    en.wikipedia.org/wiki/PDE5_inhibitor

    Chemical structure of sildenafil (Viagra), the prototypical PDE5 inhibitor. A phosphodiesterase type 5 inhibitor (PDE5 inhibitor) is a vasodilating drug that works by blocking the degradative action of cGMP-specific phosphodiesterase type 5 (PDE5) on cyclic GMP in the smooth muscle cells lining the blood vessels supplying various tissues.

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