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The Age-Related Eye Disease Study (AREDS) was a clinical trial sponsored by the National Eye Institute that ran from 1992 to 2001. [1] The study was designed to: investigate the natural history and risk factors of age-related macular degeneration (AMD) and cataracts , and
In the AREDS-2 formulation, lutein (10 mg) and zeaxanthin (2 mg) replaced beta-carotene due to the risk of lung cancer in smokers taking beta-carotene. [2] There is some evidence to indicate that people with bilateral early or intermediate AMD, or intermediate AMD in one eye and advanced AMD in the other eye may benefit from vitamin and mineral ...
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Age-Related Eye Disease Study 2 (AREDS2): This study investigated the roles of zinc and beta-carotene in the original AREDS formulation. It also examined whether adding omega-3 fatty acids and the antioxidants lutein and zeaxanthin would improve the effectiveness of the AREDS formulation. [14]
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