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Gastroenteritis is the main reason for 3.7 million visits to physicians a year in the United States [1] and 3 million visits in France. [81] In the United States gastroenteritis as a whole is believed to result in costs of US$23 billion per year, [82] with rotavirus alone resulting in estimated costs of US$1 billion a year. [1]
Sequencing is the only diagnostic method that will provide the full sequence of a virus genome. Hence, it provides the most information about very small differences between two viruses that would look the same using other diagnostic tests. Currently it is only used when this depth of information is required.
The main symptom of gastroenteritis is diarrhea. Other symptoms may include: [citation needed] Abdominal pain or cramping; Nausea; Vomiting; Low grade fever; Because of the symptoms of vomiting and diarrhea, people who have gastroenteritis can become dehydrated quickly.
A medical history, physical examination and tests such as blood counts, stool cultures, CT scans, MRIs, PCRs, colonoscopies and upper endoscopies may be used in order to perform a differential diagnosis. [9] [11] [16] [21] A biopsy may be required to obtain a sample for histopathology. [citation needed]
Most children admitted to hospital with gastroenteritis are tested for rotavirus. [95] [96] Specific diagnosis of infection with rotavirus is made by finding the virus in the child's stool by enzyme immunoassay. There are several licensed test kits on the market which are sensitive, specific and detect all serotypes of rotavirus. [97]
Source: HPA, NB Testing methods changed in 2007. [75] Norovirus causes about 18% of all cases of acute gastroenteritis worldwide. It is relatively common in developed countries and in low-mortality developing countries (20% and 19% respectively) compared to high-mortality developing countries (14%).
A diagnosis for indigestion is based on symptoms, with a possible need for more diagnostic tests. In younger patients (less than 60 years of age) without red flags (e.g., weight loss), it is recommended to test for H. pylori noninvasively, followed by treatment with antibiotics in those who test positively.
Sapovirus is a genetically diverse genus of single-stranded positive-sense RNA, non-enveloped viruses within the family Caliciviridae. [1] [2] Together with norovirus, sapoviruses are the most common cause of acute gastroenteritis (commonly called the "stomach flu" although it is not related to influenza) in humans and animals.