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Permethrin is a medication and an insecticide. [6] [7] As a medication, it is used to treat scabies and lice. [8]It is applied to the skin as a cream or lotion. [6] As an insecticide, it can be sprayed onto outer clothing or mosquito nets to kill the insects that touch them.
Insecticides used for the treatment of head lice include lindane, malathion, carbaryl, pyrethrum, piperonyl butoxide, permethrin, phenothrin, bioallethrin, and spinosad. Many of the pediculicides in the market are either not fully effective or are ineffective when they are used according to the instructions.
Permethrin exerts its therapeutic effect by disrupting sodium transport across neuronal membranes in arthropods, inducing depolarization. This mechanism ultimately leads to respiratory paralysis in the affected arthropod, establishing permethrin as a potent agent in managing scabies and pediculosis.
Treatment: Permethrin is the drug of choice for the treatment of scabies, per the CDC. Topical permethrin should be applied every two to three days for up to two weeks. Top image credit: Cixia.
Permethrin, a pyrethroid insecticide, is the most effective treatment for scabies, [39] and remains the treatment of choice. [ 15 ] [ 40 ] It is applied from the neck down, usually before sleep, and left on for about 8 to 14 hours, then washed off in the morning. [ 15 ]
Although highly toxic to cats, permethrin is recommended as protection against mosquitoes for clothing, gear, or bed nets. [13] In an earlier report, the CDC found oil of lemon eucalyptus to be more effective than other plant-based treatments, with a similar effectiveness to low concentrations of DEET. [14]
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