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Tobramycin/dexamethasone, sold under the brand name Tobradex, is a fixed-dose combination medication in the form of eye drops and eye ointment, marketed by Alcon. [ 1 ] [ 2 ] [ 3 ] The active ingredients are tobramycin (an antibiotic ) and dexamethasone (a corticosteroid ). [ 2 ]
It is a combination of loteprednol, as the etabonate, a corticosteroid; and tobramycin, an aminoglycoside antibiotic. [1] It is used as drops in the eye . [ 1 ]
ATC code S01 Ophthalmologicals is a therapeutic subgroup of the Anatomical Therapeutic Chemical Classification System, a system of alphanumeric codes developed by the World Health Organization (WHO) for the classification of drugs and other medical products.
Tobramycin is on the World Health Organization's List of Essential Medicines. [11] In 2022, tobramycin was the 281st most commonly prescribed medication in the United States, with more than 600,000 prescriptions. [12] Tobrex eye drops are a 0.3% tobramycin sterile ophthalmic solution produced by Alcon Pharmaceuticals.
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Topical antibiotic eye drops or ointment (e.g., chloramphenicol or fusidic acid) are sometimes used for the initial acute infection, but are otherwise of little value in treating a chalazion. [20] [citation needed] If they continue to enlarge or fail to settle within a few months, smaller lesions can be injected with a corticosteroid.
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