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With dose-dependent concentrations the half-life is about 12–13 hours, Tmax 1–2 hours and it is protein-bound, so the medication has a rapid absorption and minimal excretion by the kidney. [ 49 ] Dapagliflozin disposition is not evidently affected by body mass index (BMI) or body weight , therefore the pharmacokinetic findings are expected ...
GoldenEye: Source - A total conversion for Half-Life 2 that aims to recreate the original Nintendo 64 classic GoldenEye 007. It received Mod DB's "Editors' Choice for Reinvention" in 2006, [53] "Third Place, Mod of the Year" in 2006, [34] and "Fourth Place, Top Unreleased Mods" in 2005. [54] Half-Life 2: Capture the Flag - A simple capture-the ...
Deathmatch Classic – A free, official Half-Life mod by Valve that updates the multiplayer gameplay from id Software's Quake, featuring enhanced textures, models, and lighting. [4] It was released on June 7, 2001, [5] and included in an update to Half-Life a month later. [6] OS X and Linux ports of the Windows game were released through Steam ...
Half-Life 2: 2012 September 14 2020 March 6 The game is a remake of Valve's game Half-Life. Chex Quest: Doom: 1996 A total conversion of The Ultimate Doom, Chex Quest was a Chex cereal promotion aimed at children aged 6–9 and up. [10] [11] It was the first video game ever to be included in cereal boxes as a prize. [12] Chivalry: Medieval ...
In addition to Farxiga, the first drugs are Eliquis, Jardiance, Xarelto, Januvia, Entresto, Enbrel, Imbruvica and Stelara, as well as Fiasp and certain other insulins made by Novo Nordisk ...
Mods can extend the shelf life of games, such as Half-Life (1998), which increased its sales figures over the first three years of its release. According to the director of marketing at Valve, a typical shelf-life for a game would be 12 to 18 months, even if it was a "mega-hit". [ 32 ]
Boehringer Ingelheim and Eli Lilly's Jardiance is used to treat type-2 diabetes, heart failure and chronic kidney disease. It cost Medicare $7 billion for 1.6 million patients in the same period ...
Jardiance – fights Type 2 diabetes. Xarelto – used to prevent clotting. Januvia - fights Type 2 diabetes. Farxiga - fights Type 2 diabetes. Entresto - heart failure drug. Enbrel – treats ...
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