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Iodine-131 (131 I) is the most common RNT worldwide and uses the simple compound sodium iodide with a radioactive isotope of iodine. The patient (human or animal) may ingest an oral solid or liquid amount or receive an intravenous injection of a solution of the compound. The iodide ion is selectively taken up by the thyroid gland.
Iodine-131 (131 I, I-131) is an important radioisotope of iodine discovered by Glenn Seaborg and John Livingood in 1938 at the University of California, Berkeley. [3] It has a radioactive decay half-life of about eight days. It is associated with nuclear energy, medical diagnostic and treatment procedures, and natural gas production.
The patient swallows a radioisotope of iodine in the form of capsule or fluid, and the absorption (uptake) of this radiotracer by the thyroid is studied after 4–6 hours and after 24 hours with the aid of a scintillation counter. The dose is typically 0.15–0.37 MBq (4–10 μCi) of 131 I iodide, or 3.7–7.4 MBq (100–200 μCi) of 123 I ...
Iodine-131, a radioactive isotope used for thyroid imaging (scintigraphy) and therapy of thyroid cancers, can be less effective when used within two to six weeks after application of iotrolan because of residual iodine in the body. Iotrolan can slow down the excretion of the diabetes drug metformin, potentially resulting in lactic acidosis. [2]
This is a form of targeted therapy for hyperthyroidism. Since even low levels of ionizing radiation are highly mutagenic and can cause cancer, [16] less toxic iodine isotopes such as iodine-123 [17] are more commonly used in nuclear imaging, while iodine-131 is used for its cytolytic (cell-destroying) effects in hyperthyroidism and thyroid ...
Iodine is a chemical element with many uses in medicine, depending on the form. Elemental iodine and iodophors are topical antiseptics. [2] Iodine, in non-elemental form, functions as an essential nutrient in human biology (see iodine in biology). [3] Organic compounds containing iodine are also useful iodinated contrast agents in X-ray imaging ...
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One protocol is to discontinue levothyroxine, then prescribe liothyronine while the T 4 levels are falling, and finally stop the liothyronine two weeks before the radioactive iodine treatment. [ 5 ] Liothyronine may also be used for myxedema coma because of its quicker onset of action when compared to levothyroxine. [ 6 ]
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