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In this diagram of a duplicated chromosome, (2) identifies the centromere—the region that joins the two sister chromatids, or each half of the chromosome. In prophase of mitosis, specialized regions on centromeres called kinetochores attach chromosomes to spindle fibers. The centromere links a pair of sister chromatids together during cell ...
If the chromosome is a submetacentric chromosome (One arm big and the other arm small) then the centromere divides each chromosome into two regions: the smaller one, which is the p region, and the bigger one, the q region. The sister chromatids will be distributed to each daughter cell at the end of the cell division.
The Pds5 gene was also identified in yeast as necessary for the establishment of cohesion. In humans, the gene has two homologs, Pds5A and Pds5B. Pds5 interacts with chromatin-associated cohesin. Pds5 is not strictly establishment-specific, as Pds5 is necessary for maintenance of cohesion during G2 and M phase. The loss of Pds5 negates the ...
In prophase of mitosis, specialized regions on centromeres called kinetochores attach chromosomes to spindle fibers. The monocentric chromosome is a chromosome that has only one centromere in a chromosome and forms a narrow constriction. Monocentric centromeres are the most common structure on highly repetitive DNA in plants and animals. [1]
Non-sister chromatids, on the other hand, refers to either of the two chromatids of paired homologous chromosomes, that is, the pairing of a paternal chromosome and a maternal chromosome. In chromosomal crossovers , non-sister (homologous) chromatids form chiasmata to exchange genetic material during the prophase I of meiosis (See Homologous ...
Centromere: Used during cell division as the attachment point for the spindle fibers. Telomere: Used to maintain chromosomal integrity by capping off the ends of the linear chromosomes. This region is a microsatellite, but its function is more specific than a simple tandem repeat.
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The mother centriole, the older of the two in the centriole pair, also has a central role in making cilia and flagella. [10] The centrosome is copied only once per cell cycle, so that each daughter cell inherits one centrosome, containing two structures