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The first adoption study on schizophrenia published in 1966 by Leonard Heston demonstrated that the biological children of parents with schizophrenia were just as likely to develop schizophrenia whether they were reared by their parents or adopted [5] and was essential in establishing schizophrenia as being largely genetic instead of being a result of child rearing methods.
In a follow-up study, the authors tested the notion that schizophrenia is the result of a genetic by environmental interaction, that is that insults in utero may be specifically stressful to persons with a brain vulnerability to schizophrenia. In a follow-up study, Leigh Silverton and Sarnoff Mednick at the University of Southern California ...
Twin studies are part of the broader methodology used in behavior genetics, which uses all data that are genetically informative – siblings studies, adoption studies, pedigree, etc. These studies have been used to track traits ranging from personal behavior to the presentation of severe mental illnesses such as schizophrenia.
Family studies on schizophrenia were reviewed. That the disorder runs in families did not suggest it was genetically inherited, since cultural transmission occurs from parents to children. Twin and adoption studies were presented as the standard methods to disentangle contributions from genes and the environment. [36]
These methods of study later improved due to the development of more advanced clinical, epidemiological, and biometrical research tools. Better research tools were the precursor to the ability to perform valid family, twin, and adoption studies. Researchers learned that genes influence how these disorders manifest and that they tend to ...
David Rosenthal (c. 1916 – 1996) [1] was an American psychologist known for his research on the relative genetic and environmental contributions to schizophrenia and other psychopathologies. [2] He is particularly recognized for his research on the Genain quadruplets, and he led the team who studied the quadruplets intensively from 1955 to 1958.
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