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The first Iteration was prior to 1998. In 1999, the FDA released version 2.0. CTCAE version 4.0 in 2009 with an update to y version 4.03 in 2010. [2] The current version 5.0 was released on November 27, 2017. Many clinical trials, now extending beyond oncology, encode their observations based on the CTCAE system. It uses a range of grades from ...
Support for PDF version 1.3; 5.0 May 2001 Last version to support Windows 95 OSR2, Windows 98 First Edition, Windows NT 4.0 Service Pack 5, pre-Service Pack 2 Windows 2000, Mac OS 8.6 and Mac OS 9.0.4 - 9.2.2. Windows, Macintosh, Solaris, HP-UX, AIX, Linux Support for PDF version 1.4; 6.0 July 2003 Adobe Acrobat Reader was renamed to Adobe Reader.
Adobe ended the support of the Accelio version of the product in 2004. In late 2003, Designer was redesigned and released as the Adobe Forms Designer. In March 2004, Adobe shipped Adobe Designer 6.0 for use with Adobe's Intelligent Document Platform and with version 6 of the Adobe Acrobat software.
Documents containing Adobe extended features still carry the PDF base version number 1.7 but also contain an indication of which extension was followed during document creation. [21] PDF documents conforming to ISO 32000-2 carry the PDF version number 2.0, and are known to developers as "PDF 2.0 documents".
The imaging model of the Quartz graphics layer is based on the model common to Display PostScript and PDF, leading to the nickname Display PDF. The Preview application can display PDF files, as can version 2.0 and later of the Safari web browser. System-level support for PDF allows macOS applications to create PDF documents automatically ...
Starting with Ruby version 1.9.2 (released on 18 August 2010), the bug with year 2038 is fixed, [16] by storing time in a signed 64-bit integer on systems with 32-bit time_t. [ 17 ] Starting with NetBSD version 6.0 (released in October 2012), the NetBSD operating system uses a 64-bit time_t for both 32-bit and 64-bit architectures.
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