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Zinc picolinate (or ZnPic) is the zinc coordination complex derived from picolinic acid and zinc(II). It has the formula Zn(NC 5 H 4 CO 2 ) 2 (H 2 O) 2 . The complex adopts an octahedral molecular geometry , containing two bidentate picolinate ligands (conjugate base of picolinic acid) and two aquo ligands .
Structure of Zn(picolinate) 2 (H 2 O) 2. Hydrogenation of picolinic acid gives piperidine-2-carboxylic acid, a precursor to the drug Mepivacaine. Picolinic acid is a bidentate chelating agent of elements such as chromium, zinc, manganese, copper, iron, and molybdenum in the human body. [5] [6] It is a substrate in the Mitsunobu reaction.
Microencapsulation is a process in which tiny particles or droplets are surrounded by a coating to give small capsules, with useful properties. [1] [2] In general, it is used to incorporate food ingredients, [3] enzymes, cells or other materials on a micro metric scale.
The ZINC database (recursive acronym: ZINC is not commercial) is a curated collection of commercially available chemical compounds prepared especially for virtual screening. ZINC is used by investigators (generally people with training as biologists or chemists ) in pharmaceutical companies , biotechnology companies , and research universities .
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