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Antibodies to tissue transglutaminase (abbreviated as anti-tTG or anti-TG2) are found in patients with several conditions, including celiac disease, juvenile diabetes, [1] inflammatory bowel disease, [2] and various forms of arthritis.
Tissue transglutaminase (abbreviated as tTG or TG2) is a 78-kDa, ... Serology for anti-tTG antibodies has superseded older serological tests (anti-endomysium, ...
Persons suspected of having celiac disease may undergo serological testing for IgA anti-tissue transglutaminase antibodies (abbreviated anti-tTG antibodies or anti-TG2 antibodies) and anti-endomysial antibodies (abbreviated EMA) provided the IgA-level is high, and if IgA is low, testing for certain IgG antibodies; in case of positive ...
In people with duodenal lymphocytosis – following guidelines from the European Society of Pediatric Gastroenterology, Hepatology and Nutrition (ESPGHAN) – a high count of celiac disease cells (or CD/CD3 ratio) in immunohistochemical assessment of biopsies, or the presence of IgA anti-TG2 [13] [7] and/or anti-endomysial [7] intestinal ...
The news outlet reports the medication works using monoclonal antibodies that block the activity of nerve growth factor, a protein that helps transmit pain signals in the body.
Anti-transglutaminase antibodies are found in celiac disease and may play a role in the small bowel damage in response to dietary gliadin that characterises this condition. [2] In the related condition dermatitis herpetiformis , in which small bowel changes are often found and which responds to dietary exclusion of gliadin-containing wheat ...
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