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An equianalgesic chart is a conversion chart that lists equivalent doses of analgesics (drugs used to relieve pain). Equianalgesic charts are used for calculation of an equivalent dose (a dose which would offer an equal amount of analgesia) between different analgesics. [1]
For comparison, those with a V d L/kg body weight of less than 0.2 are mainly distributed in blood plasma, 0.2-0.7 mostly in the extracellular fluid and those with more than 0.7 are distributed throughout total body water.
The toxic dose of paracetamol is highly variable. In general the recommended maximum daily dose for healthy adults is 4 grams. [17] [18] Higher doses lead to increasing risk of toxicity. In adults, single doses above 10 grams or 200 mg/kg of bodyweight, whichever is lower, have a reasonable likelihood of causing toxicity.
1.0 long cwt (110 lb; 51 kg) short hundredweight: short cwt short cwt 1.0 short cwt (100 lb; 45 kg) long quarter: long qtr long qtr 1.0 long qtr (28 lb; 13 kg) short quarter: short qtr short qtr 1.0 short qtr (25 lb; 11 kg) stone: st st 14 lb used mostly in the British Commonwealth except Canada 1.0 st (14 lb; 6.4 kg) st kg. st kg lb; st lb
Paracetamol's bioavailability is dose-dependent: it increases from 63 % for 500 mg dose to 89 % for 1000 mg dose. [6] Its plasma terminal elimination half-life is 1.9–2.5 hours, [ 6 ] and volume of distribution is roughly 50 L. [ 132 ] Protein binding is negligible, except under the conditions of overdose, when it may reach 15–21 %. [ 6 ]
DETROIT (Reuters) -U.S. automakers Ford Motor and General Motors will donate $1 million each, along with vehicles, to U.S. President-elect Donald Trump's January inauguration, company ...
The average adult should consume at least 0.35 grams of protein per pound of body weight daily to maintain their existing muscle mass and promote overall health, according to the The Academy of ...
For the drugs administered by oral and dermal route, the units of threshold dose are mg/kg body-weight/day (dose of the drug in mg per body weight in kg per day) or ppm (parts per million), while the threshold dose of drugs by inhalation delivery has the unit of mg/L 6h/day (amount of drug in mg in 1L of air, for 6 hours per day). [8]