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  2. Cortisol awakening response - Wikipedia

    en.wikipedia.org/wiki/Cortisol_awakening_response

    Waking up earlier in the morning increases the response. [11]Shift work: nurses working on morning shifts with very early awakening (between 4:00–5:30 a.m.) had a greater and prolonged cortisol awakening response than those on the late day shift (between 6:00–9:00 a.m.) or the night shift (between 11:00 a.m.–2:00 p.m.). [12]

  3. Nonsteroidal anti-inflammatory drug - Wikipedia

    en.wikipedia.org/wiki/Nonsteroidal_anti...

    These NSAIDs, while reducing inflammation, also inhibit platelet aggregation and increase the risk of gastrointestinal ulcers and bleeds. [11] COX-2 selective inhibitors have fewer gastrointestinal side effects, but promote thrombosis , and some of these agents substantially increase the risk of heart attack .

  4. Anti-inflammatory - Wikipedia

    en.wikipedia.org/wiki/Anti-inflammatory

    In whole, the NSAIDs prevent the prostaglandins from ever being synthesized, reducing or eliminating the inflammation and resulting pain. [citation needed] Some common examples of NSAIDs are aspirin, ibuprofen, and naproxen. The newer specific COX-inhibitors are not classified together with the traditional NSAIDs, even though they presumably ...

  5. 8 Ways to Get Arthritis Pain Relief Naturally - AOL

    www.aol.com/8-ways-arthritis-pain-relief...

    Arthritis can be uncomfortable, but you don't have to just suffer through it. Try these doctor-recommended arthritis pain relief options.

  6. Ibuprofen - Wikipedia

    en.wikipedia.org/wiki/Ibuprofen

    [86] [87] As with other NSAIDs, ibuprofen may be useful in the treatment of severe orthostatic hypotension (low blood pressure when standing up). [88] NSAIDs are of unclear utility in the prevention and treatment of Alzheimer's disease. [89] [90] Ibuprofen has been associated with a lower risk of Parkinson's disease and may delay or prevent it.

  7. Corticosteroid - Wikipedia

    en.wikipedia.org/wiki/Corticosteroid

    The neuropsychiatric effects are partly mediated by sensitization of the body to the actions of adrenaline. Therapeutically, the bulk of corticosteroid dose is given in the morning to mimic the body's diurnal rhythm; if given at night, the feeling of being energized will interfere with sleep. An extensive review is provided by Flores and Gumina ...

  8. These vascular risks are strongly associated with severe ...

    www.aol.com/news/controlling-three-things...

    High blood pressure, also known as hypertension, can result from an unhealthy lifestyle or certain health conditions, such as diabetes or obesity. The condition can also occur during pregnancy ...

  9. COX-inhibiting nitric oxide donator - Wikipedia

    en.wikipedia.org/wiki/COX-inhibiting_nitric...

    The importance of developing such drugs was increased when COX-2-specific NSAIDs rofecoxib (Vioxx) and lumiracoxib (Prexige) were removed from major pharmaceutical markets in the mid-2000s due to vascular safety concerns. In addition, traditional NSAIDs increase blood pressure and interfere with the actions of antihypertensive drugs.