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Triamterene directly blocks the epithelial sodium channel [4] (ENaC) on the lumen side of the kidney collecting tubule. [5]: 127 Other diuretics cause a decrease in the sodium concentration of the forming urine due to the entry of sodium into the cell via the ENaC, and the concomitant exit of potassium from the principal cell into the forming urine.
Kidney stones can result from an ... can be a contributing cause of kidney stones in up to 2/3 of cases. ... of stones is the thiazide and thiazide-like diuretics, ...
Additionally, hypercalciuria can contribute to kidney stone formation which may present with flank or back pain that comes and goes. It can be painful to pass kidney stones and in extreme cases cause kidney damage. [2] [3] Patients that both form kidney stones and have hypercalciuria are at increased risk for bone loss leading to osteoporosis. [4]
There are a number of things that form kidney stones. Those with diseases like high blood pressure, diabetes, and obesity have a higher risk of having kidney stones. Causes of kidney stones can ...
These conditions can cause nephrocalcinosis in association with hypercalciuria without hypercalcaemia: [citation needed] Distal renal tubular acidosis; Medullary sponge kidney; Neonatal nephrocalcinosis and loop diuretics; Inherited tubulopathies; Chronic hypokalemia; Beta thalassemia
Hypercalcemia usually causes symptoms that lead to chronic dehydration, such as nausea, vomiting, anorexia, and nephrogenic diabetes insipidus (inability of the kidney to concentrate the urine). IV fluid rehydration allows the kidneys to excrete more calcium, and usually lowers the calcium level by 1–2 mg/dL.
Chronic kidney disease. Kidney stones. ... Having high levels of uric acid in the body can cause gout in the feet or other lower-body joints. ... and diuretics. Lastly, dietary factors also ...
Thiazide therapy has proven effective in preventing the formation of kidney stones, reducing urinary calcium, and preventing the periodic occurrence of nephrolithiasis. [8] Thiazides lessen urinary citrate excretion and blood potassium levels, making it recommended to prescribe potassium citrate alongside thiazide therapy. [ 3 ]