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  2. Dermis - Wikipedia

    en.wikipedia.org/wiki/Dermis

    The dermis is composed of three major types of cells: [3] fibroblasts, macrophages, and mast cells.. Apart from these cells, the dermis is also composed of matrix components such as collagen (which provides strength), elastin (which provides elasticity), and extrafibrillar matrix, an extracellular gel-like substance primarily composed of glycosaminoglycans (most notably hyaluronan ...

  3. Dermoepidermal junction - Wikipedia

    en.wikipedia.org/wiki/Dermoepidermal_junction

    H&E stained section of human skin. The dermoepidermal junction or dermal-epidermal junction (DEJ) is the interface between the epidermal and the dermal layers of the skin. The basal cells of the epidermis connect to the basement membrane by the anchoring filaments of hemidesmosomes; the cells of the papillary layer of the dermis are attached to the basement membrane by anchoring fibrils, which ...

  4. Loose connective tissue - Wikipedia

    en.wikipedia.org/wiki/Loose_connective_tissue

    The papillary dermis consists of loose connective tissue. Details; Identifiers; ... mesh-like tissue with a fluid matrix and functions to cushion and protect body organs.

  5. Human skin - Wikipedia

    en.wikipedia.org/wiki/Human_skin

    The papillary region is composed of loose areolar connective tissue. It is named for its finger-like projections called papillae, which extend toward the epidermis. The papillae provide the dermis with a "bumpy" surface that interdigitates with the epidermis, strengthening the connection between the two layers of skin.

  6. List of skin conditions - Wikipedia

    en.wikipedia.org/wiki/List_of_skin_conditions

    The dermis is the layer of skin between the epidermis and subcutaneous tissue, and comprises two sections, the papillary dermis and the reticular dermis. [10] The superficial papillary dermis interdigitates with the overlying rete ridges of the epidermis, between which the two layers interact through the basement membrane zone. [10] Structural ...

  7. Integumentary system - Wikipedia

    en.wikipedia.org/wiki/Integumentary_system

    The dermis has two layers: the papillary dermis and the reticular layer. The papillary layer is the superficial layer that forms finger-like projections into the epidermis (dermal papillae), [5] and consists of highly vascularized, loose connective tissue. The reticular layer is the deep layer of the dermis and consists of the dense irregular ...

  8. Langerhans cell - Wikipedia

    en.wikipedia.org/wiki/Langerhans_cell

    They also occur in the papillary dermis, particularly around blood vessels, [4] as well as in the mucosa of the mouth, foreskin, and vaginal epithelium. [5] They can be found in other tissues, such as lymph nodes , particularly in association with the condition Langerhans cell histiocytosis (LCH).

  9. Skin - Wikipedia

    en.wikipedia.org/wiki/Skin

    The dermis is the layer of skin beneath the epidermis that consists of connective tissue and cushions the body from stress and strain. The dermis provides tensile strength and elasticity to the skin through an extracellular matrix composed of collagen fibrils , microfibrils , and elastic fibers , embedded in hyaluronan and proteoglycans . [ 15 ]