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The treatment of choice in any patient with BAC is complete surgical resection, typically via lobectomy or pneumonectomy, with concurrent ipsilateral lymphadenectomy. [ 16 ] Non-mucinous BAC are highly associated with classical EGFR mutations, and thus are often responsive to targeted chemotherapy with erlotinib and gefitinib.
Obstructive lung disease is a category of respiratory disease characterized by airway obstruction.Many obstructive diseases of the lung result from narrowing (obstruction) of the smaller bronchi and larger bronchioles, often because of excessive contraction of the smooth muscle itself.
When isolated bronchial carcinoids are diagnosed, oncology guidelines recommend surgical resection with lymph node sampling. [10] However, as multiple carcinoids may develop in the setting of DIPNECH, a more conservative approach is often considered to preserve lung function. [citation needed]
In “Type 2” the bronchus is contained in the tumor. These types are more common in malignant nodules. A compressed and narrowed bronchus is defined as “Type 3”, and can occur in both benign and malignant nodules. Narrowing of the proximal bronchial tree is described as “type 4” and is associated with malignancy.
It is the second most prevalent type of lung cancer after lung adenocarcinoma and it originates in the bronchi. Its tumor cells are characterized by a squamous appearance, similar to the one observed in epidermal cells. Squamous-cell carcinoma of the lung is strongly associated with tobacco smoking, more than any other forms of NSCLC. [1]
Lung cancer, also known as lung carcinoma, is a malignant tumor that begins in the lung. Lung cancer is caused by genetic damage to the DNA of cells in the airways, often caused by cigarette smoking or inhaling damaging chemicals. Damaged airway cells gain the ability to multiply unchecked, causing the growth of a tumor.
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A lobule of the lung enclosed in septa and supplied by a terminal bronchiole that branches into the respiratory bronchioles. Each respiratory bronchiole supplies the alveoli held in each acinus accompanied by a pulmonary artery branch. The pulmonary lobule is the portion of the lung ventilated by one bronchiole.