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Cryopreservation of ovarian tissue is of interest to women who want fertility preservation beyond the natural limit, or whose reproductive potential is threatened by cancer therapy, [1] for example in hematologic malignancies or breast cancer. [2]
The main methods of fertility preservation are ovarian protection by GnRH agonists, cryopreservation of ovarian tissue, eggs or sperm, or of embryos after in vitro fertilization. [16] The patient may also choose to use egg or sperm from a donor by third party reproduction rather than having biological children.
An artificial ovary is a potential fertility preservation treatment that aims to mimic the function of the natural ovary. Conventional fertility preservation for females involves oocyte cryopreservation or ovarian tissue cryopreservation. However, there are drawbacks to these treatments.
The therapy, Elahere, was being tested in patients with a type of cancer that affects the ovaries, fallopian tube or walls of the abdomen, and who have received at least two prior lines of treatment.
Assisted reproductive technology (ART) includes medical procedures used primarily to address infertility.This subject involves procedures such as in vitro fertilization (IVF), intracytoplasmic sperm injection (ICSI), cryopreservation of gametes or embryos, and/or the use of fertility medication.
Scientists have created an "atlas" of ovarian aging. The atlas suggests ovaries are an untapped, rapid way to study human longevity treatments. One researcher is testing antiaging drugs on ovaries ...
Cryopreservation or cryoconservation is a process where biological material - cells, tissues, or organs - are frozen to preserve the material for an extended period of time. [1] At low temperatures (typically −80 °C (−112 °F) or −196 °C (−321 °F) using liquid nitrogen ) any cell metabolism which might cause damage to the biological ...
TVOR is typically performed after ovarian hyperstimulation, where oocytes are pharmacologically stimulated to mature. When the ovarian follicles have reached a certain degree of development, induction of final oocyte maturation is performed, generally by an intramuscular or subcutaneous injection of human chorionic gonadotropin (hCG). [10]