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2. FDA Issues Urgent Warning on Dangers of Common Dog Medication

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   The United States Food and Drugs Administration is warning pet owners about a common medication given to pets to treat arthritis. The F.D.A. now says that the drug Librela may be associated with ...

3. Early Results Of Dog Longevity Treatment Show Promise - AOL

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   "The goal of that clinical trial is to determine whether or not the drug Rapamycin can slow aging, increase lifespan and improve healthspan in pet dogs," he said. Rapamycin is a drug primarily ...

4. Dog Aging Project - Wikipedia

   en.wikipedia.org/wiki/Dog_Aging_Project

   Chemical structure of rapamycin, a pharmaceutical under evaluation for its effects on longevity. The project engages the general public to register their dogs in the studies, and therefore the project is an example of citizen science. [3] As of 2022 nearly 40,000 dogs have been registered with the project. [1]

5. Sirolimus - Wikipedia

   en.wikipedia.org/wiki/Sirolimus

   Serious side effects including hypersensitivity and swelling have been observed in renal transplant patients. [22] While sirolimus was considered for treatment of LAM, it received orphan drug designation status because LAM is a rare condition. [22] The safety of LAM treatment by sirolimus in people younger than 18 years old has not been tested.

6. mTOR inhibitors - Wikipedia

   en.wikipedia.org/wiki/MTOR_inhibitors

   mTOR inhibitors are a class of drugs used to treat several human diseases, including cancer, autoimmune diseases, and neurodegeneration. They function by inhibiting the mammalian target of rapamycin (mTOR) (also known as the mechanistic target of rapamycin), which is a serine/threonine-specific protein kinase that belongs to the family of phosphatidylinositol-3 kinase (PI3K) related kinases ...

7. Why I Started and Stopped Taking the “Anti-Aging” Drug Rapamycin

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   By 2006, an extensive body of work from several independent studies, including studies from yeast to mammals, all pointed to rapamycin as having an anti-aging effect or at least slowing down the ...