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A formal survey of dextromethorphan users [25] showed that more than half of users reported experience of these withdrawal symptoms individually for the first week after long-term/addictive dextromethorphan use: fatigue, apathy, flashbacks, and constipation. Over a quarter reported insomnia, nightmares, anhedonia, impaired memory, attention ...
Dextromethorphan, sold under the brand name Robitussin among others, is a cough suppressant used in many cough and cold medicines. [6] In 2022, the US Food and Drug Administration (FDA) approved the combination dextromethorphan/bupropion to serve as a rapid-acting antidepressant in people with major depressive disorder.
Dextromethorphan/bupropion has less activity as an NMDA receptor antagonist than dextromethorphan alone. [11] This is because bupropion is a potent CYP2D6 inhibitor and prevents the bioactivation of dextromethorphan into dextrorphan , a much more potent NMDA receptor antagonist and weaker serotonin reuptake inhibitor than dextromethorphan ...
Ketamine’s antidepressant effects are part of what prompted researchers to explore other drugs that target glutamate—like the venerable cough suppressant dextromethorphan found in Robitussin ...
On Monday, Axsome Therapeutics, Inc. (NASDAQ:AXSM) released data from ACCORD-2, ADVANCE-2, and long-term safety trials AXS-05 (dextromethorphan-bupropion) in Alzheimer's disease agitation. The ...
DayQuil Cough (dextromethorphan) DayQuil Cold & Flu (acetaminophen, dextromethorphan, phenylephrine) DayQuil Severe Cold & Flu (acetaminophen, dextromethorphan, guaifenesin, phenylephrine) DayQuil Mucus Control DM (dextromethorphan, guaifenesin) Dayquil Sinex (acetaminophen, phenylephrine, or oxymetazoline) Parent: Vicks
In a mouse study, researchers found that zolpidem (Ambien), a common sleep aid, could prevent the brain from effectively clearing up 'waste', though it remains unclear whether this could affect ...
The provider of a dextromethorphan containing product must acquire proof of age if they believe that the potential purchaser is below the age of 18. Any person found to possess more than one gram of pure dextromethorphan without the required credentials is subject to a $1000 fine for the first offense and a $2500 fine for each subsequent offense.
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