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Graphic depicting the human skin microbiota, with relative prevalences of various classes of bacteria. The human microbiome is the aggregate of all microbiota that reside on or within human tissues and biofluids along with the corresponding anatomical sites in which they reside, [1] [2] including the gastrointestinal tract, skin, mammary glands, seminal fluid, uterus, ovarian follicles, lung ...
The microbiome and host emerged during evolution as a synergistic unit from epigenetics and genetic characteristics, sometimes collectively referred to as a holobiont. [7] [8] The presence of microbiota in human and other metazoan guts has been critical for understanding the co-evolution between metazoans and bacteria.
In the context of genomics, the term human microbiome is sometimes used to refer to the collective genomes of resident microorganisms; [154] the term human metagenome has the same meaning. [153] Humans are colonised by many microorganisms, with approximately the same order of magnitude of non-human cells as human cells. [155]
At that time, biology was focused on macroorganisms. Later, with the advent of microscopy, the new discovered ubiquitous microorganisms were fit in this system. Then, Fauna included moving organisms (animals and protist as "micro-fauna") and Flora the organisms with apparent no movement (plants/fungi; and bacteria as "microflora").
The Human Microbiome Project (HMP) was a United States National Institutes of Health (NIH) research initiative to improve understanding of the microbiota involved in human health and disease. Launched in 2007, [ 1 ] the first phase (HMP1) focused on identifying and characterizing human microbiota.
The oral microbiota consists of all the microorganisms that exist in the mouth. It is the second largest of the human body and made of various bacteria, viruses, fungi and protozoa. [ 14 ] These organisms play an important role in oral and overall health.
In humans, gut microecology is the study of the microbial ecology of the human gut which includes gut microbiota composition, its metabolic activity, and the interactions between the microbiota, the host, and the environment. [3] Research in human gut microecology is important because the microbiome can have profound effects on human health.
Skin flora, also called skin microbiota, refers to microbiota (communities of microorganisms) that reside on the skin, typically human skin. Many of them are bacteria of which there are around 1,000 species upon human skin from nineteen phyla .