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Lupus erythematosus is a collection of autoimmune diseases in which the human immune system becomes hyperactive and attacks healthy tissues. [1] Symptoms of these diseases can affect many different body systems, including joints, skin, kidneys, blood cells, heart, and lungs. The most common and most severe form is systemic lupus erythematosus.
SLE significantly increases the risk of cardiovascular disease, with this being the most common cause of death. [5] While women with lupus have higher risk pregnancies, most are successful. [1] Rate of SLE varies between countries from 20 to 70 per 100,000. [2] Young women are affected about nine times more often than men. [5]
The Centers for Disease Control and Prevention estimates that more than 200,000 people in the U.S. have lupus, though the Lupus Foundation of America puts the total much higher: roughly 1.5 ...
Systemic lupus erythematosus (SLE) is one of the most common causes of cerebritis as it is believed that more than half of the patients with lupus from the United States suffer from a degree or another of lupus cerebritis. The exact pathophysiological process of lupus cerebritis is unknown.
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Lupus is tricky to diagnose, but most people with this autoimmune disease experience achy joints and swelling. The Lupus Foundation of America estimates at least 1.5 million people are living with ...
The World Health Organization has divided lupus nephritis into five stages based on the biopsy. This classification was defined in 1982 and revised in 1995. [10] [11] Class IV disease (Diffuse proliferative nephritis) is both the most severe, and the most common subtype. Class VI (advanced sclerosing lupus nephritis) is a final class which is ...
The cause of diffuse proliferative glomerulonephritis (DPGN) depends on the severity of the disease. DPGN is a secondary disease, in that a disease that a patient already has causes DPGN to occur. The most common associated disease of DPGN is severe systemic lupus erythematosus(SLE). [4] Specifically, Lupus nephritis class IV. [5]
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