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High-dose chemotherapy (HDC) is a regimen of chemotherapy medicines given at larger dosages. This therapeutic strategy is used to treat some cancers, especially those that are aggressive or have a high chance of coming back. With increased doses of chemotherapy chemicals administered to the body, HDC seeks to optimize the death of cancer cells.
Cancer chemotherapy. Wiley-Blackwell. ISBN 978-0-470-09254-5. Wood, Miriam; David Brighton (2005). The Royal Marsden Hospital handbook of cancer chemotherapy: a guide for the multidisciplinary team. St. Louis, Mo: Elsevier Churchill Livingstone. ISBN 978-0-443-07101-0. Fergus Macbeth; Hanna, Louise; Crosby, Tom (2008). Practical clinical ...
A chemotherapy regimen is a regimen for chemotherapy, defining the drugs to be used, their dosage, the frequency and duration of treatments, and other considerations. In modern oncology, many regimens combine several chemotherapy drugs in combination chemotherapy. The majority of drugs used in cancer chemotherapy are cytostatic, many via ...
For example, assuming a 99% kill per cycle of chemotherapy, a tumor of 10 11 cells would be reduced to less than one cell with six treatment cycles: 10 11 * 0.01 6 < 1. [3] However, the tumor can also re-grow during the intervals between treatments, limiting the net reduction of each fractional kill.
This is a list of chemotherapeutic agents, also known as cytotoxic agents or cytostatic drugs, that are known to be of use in chemotherapy for cancer. This list is organized by type of agent, although the subsections are not necessarily definitive and are subject to revision.
Chemotherapy may be given with a curative intent (which almost always involves combinations of drugs), or it may aim only to prolong life or to reduce symptoms (palliative chemotherapy). Chemotherapy is one of the major categories of the medical discipline specifically devoted to pharmacotherapy for cancer, which is called medical oncology. [1] [2]
Cancer treatments are a wide range of treatments available for the many different types of cancer, with each cancer type needing its own specific treatment. [1] Treatments can include surgery, chemotherapy, radiation therapy, hormonal therapy, targeted therapy including small-molecule drugs or monoclonal antibodies, [2] and PARP inhibitors such as olaparib. [3]
Revici's Guided Chemotherapy – a practice in which a chemical mixture (usually including lipid alcohol and various metals) is given by mouth or injection, supposedly to cure cancer. The practice was devised by Emanuel Revici (1896–1997) and differs from modern chemotherapy despite being named with the same term.
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