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Examining colonial morphology is the first step in the identification of an unknown microbe. The systematic assessment of the colonies' appearance, focusing on aspects like size, shape, colour, opacity, and consistency, provides clues to the identity of the organism, allowing microbiologists to select appropriate tests to provide a definitive ...
Prior to 1950, few reports were made on laboratory-acquired infections, due to the lower level of awareness concerning the problem. In 1951, a paper from Sulkin and Pike presented data on viral infections contracted in laboratories, which advised caution on handling viruses in laboratory environments and brought public awareness to the issue.
A microbiological culture, or microbial culture, is a method of multiplying microbial organisms by letting them reproduce in predetermined culture medium under controlled laboratory conditions. Microbial cultures are foundational and basic diagnostic methods used as research tools in molecular biology .
Diagnostic microbiology is the study of microbial identification. Since the discovery of the germ theory of disease , scientists have been finding ways to harvest specific organisms. Using methods such as differential media or genome sequencing , physicians and scientists can observe novel functions in organisms for more effective and accurate ...
A laboratory specimen is sometimes a biological specimen of a medical patient's tissue, fluids, or other samples used for laboratory analysis to assist in differential diagnosis or staging of a disease process. These specimens are often the most reliable method of diagnosis, depending on the ailment.
For example, when carbohydrates are fermented, the pH within the well decreases and that is indicated by a change in the color of the pH indicator. All test results are compiled to obtain a profile number, which is then compared with profile numbers in a commercial codebook (or online) to determine the identification of the bacterial species.
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What do all the unknown proteins do? Two decades since the first eukaryotes were sequenced, the "biological role" of around 20% of proteins are still unknown. [10] Many of these proteins are conserved across most eukaryotic species and some are conserved in bacteria, indicating a role fundamental for life. [10] [11] [12] Determinants of cell size.